Now-a-days there are countless way to update your twitter account.Here i listed different possible ways to Update your twitter account.
Desktop:
Twhirl – Twhirl is probably the most popular desktop client. It also supports TwitPic, TweetScan, FriendFeed.
Spaz – Desktop client for Mac, Windows and Linux
Twitteroo - Displays updates without pictures (for better or worse).
Witty – Open source client for Vista and XP
Tweetr - Allows you to send files to other Tweeters. It also has a built in webcam feature.
Alert Thingy – Keeps you updated on FriendFeed and Twitter. Allows you to easy upload pictures to Flickr.
TweetDeck – Better organize your Twitter friends with a great built in group feature.
bTT - Non-Adobe AIR based desktop client.
Twitterlicious - Minimalist desktop client.
Snitter – Customizable desktop client for Mac and Windows.
Feedalizr – Post to FriendFeed, Twitter, Jaiku and Flickr with this desktop client.
Posty - Has support for several microblogging services
Mobile:
Twitter2go-Post updates from your mobile
Firefox Plugins:
twitbin- Creates a sidebar for Firefox to keep you updated.
TwitterBar – Post updates from your address bar.
TwitterFox – Puts an icon on your bottom bar that gives you notifications and allows you to update.
TwittyTunes – Show people what you are listening to.
Online Services:
Twitterfeed – Update Twitter with new posts from your blog.
Brightkite – Brightkite updates can be synced to update Twitter as well.
Twitio.us – Twitter + Del.icio.us
Twitthat – Bookmarklet that lets you Twit about the web pages you are viewing.
HelloTxt – Update all your services in one place
Ping.fm – Updates multiple mircoblogging services
PingTwitter – Send updates when your blog updates
Socialthing – Lifestream plus ability to update.
Sendible – Organize your online life
The above listed are i collected around the web. If i miss or want to share any other ways to update twitter, Please share it in the comment 
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